Studies hint that over-the-counter treatments could be effective against COVID-19

first_imgIn past results, mostly taken from smaller groups like infected passengers on the ill-fated Diamond Princess cruise ship, about half of all patients were asymptomatic. That number has frequently been used when working out the potential spread of COVID-19. Some researchers and politicians (especially politicians) have even projected much higher numbers of asymptomatic carriers to support specific theories or actions. If only a quarter of COVID-19 patients are asymptomatic, that may mean that the threat represented by asymptomatic carriers is smaller than has been estimated. It would also mean that calculations setting the number of cases far above the number of positive tests based on the idea that many of the infected never developed symptoms could also be way off.The U.K. is also host to the massive RECOVERY project, a set of interlocking COVID-19 studies that has helped to both show that Trump’s beloved hydroxychloroquine is ineffective, and that the steroid dexamethasone helps patients receiving breathing assistance. On Tuesday, PharmaTimes reported RECOVERY was about to test the efficacy of something else: aspirin.The idea that aspirin might be helpful against COVID-19 has been debated since very early in the pandemic. Last February, researchers in China announced that they were beginning trials of using aspirin as part of COVID-19 treatment with expectations that it could help with the damage COVID-19 can cause to both the blood vessels and the lungs, and early results appeared positive. Since then, many hospitals around the world have incorporated this most common of drugs into their COVID-19 regime—but it’s far from universal. – Advertisement – By doing a deep dive into patient data—including both those who had COVID-19 and those who did not—researchers discovered that those reporting regular use of melatonin had a 30% lower rate of testing positive for COVID-19. That seems like a fairly fantastic result … but it heaps up over a large dataset even when adjusted for other factors. And here’s something that seems to really stand out: For Black patients in the study, melatonin use seemed to cut the odds of being infected by COVID-19 in half. This type of study is notorious for drawing a statistical connection between unrelated items, and there could easily be coincidental causes behind this data. Maybe people who take melatonin take better care of their health in general. Maybe they’re just better rested. In any case, additional sources are now being examined to see if similar results can be found.Finally, a drug that’s not over-the-counter but definitely seems appropriate for 2020 may also turn out to be an unexpected COVID-19 fighter. In a study published today in JAMA, researchers at Washington University in St. Louis found that patients receiving the antidepressant fluvoxamine were much less likely to develop serious COVID-19 symptoms when compared to those receiving a placebo. How much less likely is hard to say … because it appears to be infinite. As in none of the fluvoxamine patients displayed worsening conditions during the study. That’s a fantastic result … but it was also a very small study. So small that it’s not likely to change treatment regimens. However, if an antidepressant seems like a strange treatment for a virus, note that fluvoxamine is a group known as “Selective Serotonin Reuptake Inhibitors” (SSRIs), which have a powerful effect on inflammation.Aspirin, melatonin, SSRIs … they may not seem like the most obvious tools to use against a virus that has proven to be so deadly. But they have the advantage of being extremely widely used and well-understood.Big note: I’m not a doctor. This article should not be taken as medical advice. Don’t begin taking new medications without checking in with your health provider. Thanks. In October, a study published in Anesthesia and Analgesia looked at 412 patients. Of those, 76% did not get aspirin, and 24% got low-dose aspirin, the same kind often taken by heart patients. Patients who received low-dose aspirin were 44% less likely to end up on a ventilator and 43% less likely to require admission to the ICU. The number of patients studied was small, but those results are more than dramatic enough to indicate why RECOVERY is taking another look at a drug that really has been considered a “miracle” before. The very broad effects of aspirin—fever lowering, reducing clumping of platelets, lowering inflammation—may be a good match to the broad spectrum of symptoms caused by the coronavirus.But aspirin isn’t the only off-the-shelf product to generate new interest from coronavirus researchers. As Science News reports, researchers at the Cleveland Clinic found evidence that there’s another widely available product that might be a big positive when it comes to COVID-19. In this case, while it’s often seen in the form of a pill, it’s not really a drug; it’s the sleep-regulating hormone melatonin. Melatonin is naturally produced in the body each evening, with production rising as light decreases. When people take synthetic melatonin (in pills that range usually range from 1 mg to dosages far above the generally recommended limit of about 5 mg) it has a pair of sleep-inducing effects.- Advertisement –center_img The University of Bristol reports that it has completed an antibody survey of the “Children of the 90s” community spanning just under 5,000 participants. This group represents a number of British families who had—you guessed it—children in the 1990s. Health researchers have been following both the parents and the children through their lives, so they have a great deal of information on both their health history and personal habits. So their COVID-19 data could be particularly telling.In the latest survey, 4.3% of those tested had developed antibodies to COVID-19. These people were twice as likely to be from the “children” group as the “parents” group. However, even though most of the people who had COVID-19 at some point were under 30—the group generally thought to have the mildest cases of the disease—only about 25% of all participants reported being asymptomatic. – Advertisement –last_img read more

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DOC-Swan Hunter Opens Storage and Spooling Yard in Vlissingen

first_imgFollowing the equipment load-in and commissioning period, the DOC-Swan Hunter Storage and Spooling Yard in Vlissingen, the Netherlands, is ready for operations. The yard will serve as a strategic cable hub enabling product storage and spooling operations for cable manufacturers and installation contractors, as well as deep water berthing for installation and construction vessels.According to Swan Hunter, DOC’s business links with heavy transportation vessels in the Far East, combined with the company’s equipment, can also offer clients streamlined cable transportation solutions.The current yard setup includes a 5500Te basket carousel capable of over 7000Te onshore capacity, a loading tower combined with 10Te spooling tensioner, a 15Te shore tensioner and a range of spooling chutes and track ways.Director Gerard Kroese said: “This is a promising forward step for the Dutch Offshore Contractors and Swan Hunter partnership. Utilising our equipment assets onshore and offshore highlights both our capability and commitment in offering clients a full service solution with on and offshore support in the offshore renewables supply chain.”The yard and equipment spread will be utilised for a cable storage project shortly, and the DOC-Swan Hunter partnership will supplement the storage capacity with additional carousels that are currently under construction, Swan Hunter said.last_img read more

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Sumner Roundup: Wellington varsity lose, JV win, plus county scores

first_imgB. Plaine1371013—43 Cunningham1010714—41 Wellington7667—26 Oxford1512915—51 Cunningham26132513—77 South Haven17191113—60 G. Plain89820—45 Belle Plaine — B. Gooch 8, Q. Hervey 7, G. Schnieder 7, B. Gann 6, A. Johnson 6, C. Throop 5, T. Balsters 2, T. Balsters 2,Trinity Academy — R. Miller 17, T. Burns 9, B. Mosley 7, P. Miller 4, J. Loon 2,Conway Springs 51, Garden Plain 40 Belle Plaine — D. Balzer 14, K. Ast 9, B. Balsters 7, K. Ast 4, C. Myers 3, C. Ryherd 2, A. Evans 2,Trinity Academy — S. Miller 20, C. Zielke 15, W. Guetersloh 8, A. Shimp 8, A. Burns 5, K. Miller 2, K. Henderson 2, E. Alexander 2, K. Schrag 2, M. Hollinger 2,Garden Plain 45, Conway Springs 42 Andale21102017—68 C. Springs781017—42 Cedar Vale101886—32 Cunningham: H. Kerschen 10, Vierthaler 4, Ke. Ricke 22, Ko. Ricke 5. Totals 12 (6) 11-20 41.Argonia: Fitch 5, Gaddie 13, Drouhard 3, Peetoom 20, Hessman 15, Allen 11. Totals 27 (2) 11-15 67. By Tracy McCue, Sumner Newscow — Neither the Wellington varsity boys or girls basketball teams had much offensive success against Andale in the home and league opener at Crusader gymnasium.Wellington girls lost 37-20 while the boys followed suit with a 68-26 loss. Both teams are 0-1 in the Ark Valley-Chisholm Trail League Division 4.The Wellington JV teams were much more successful against Andale with the boys and girls winning.Across Sumner County, Conway Springs boys, Oxford boys and Argonia girls picked up wins.The box scores involving Sumner County teams are as follows: Wellington scoresVarsity Girls: Andale 37 Wellington 20Andale 7 7 10 13 — 37Wellington 5 6 2 7— 20Andale:R. Eck 2, J. Eck 3, Meyer 20, Rowland 2, Maxwell 2, Rowland 6, Ebert 2. Total: 10 (2) 8-14 37.Wellington: Cornejo 9, Jenkins 5, Whaley 2, Shields 2, Lewellen 2. Total: 7 (1) 3-6 20.Varsity Boys: Andale 68, Wellington 26 G. Plain981013—40 Close Forgot password? Please put in your email: Send me my password! Close message Login This blog post All blog posts Subscribe to this blog post’s comments through… RSS Feed Subscribe via email Subscribe Subscribe to this blog’s comments through… RSS Feed Subscribe via email Subscribe Follow the discussion Comments Logging you in… Close Login to IntenseDebate Or create an account Username or Email: Password: Forgot login? Cancel Login Close WordPress.com Username or Email: Password: Lost your password? Cancel Login Dashboard | Edit profile | Logout Logged in as Admin Options Disable comments for this page Save Settings You are about to flag this comment as being inappropriate. Please explain why you are flagging this comment in the text box below and submit your report. The blog admin will be notified. Thank you for your input. There are no comments posted yet. Be the first one! Post a new comment Enter text right here! Comment as a Guest, or login: Login to IntenseDebate Login to WordPress.com Login to Twitter Go back Tweet this comment Connected as (Logout) Email (optional) Not displayed publicly. Name Email Website (optional) Displayed next to your comments. Not displayed publicly. If you have a website, link to it here. Posting anonymously. Tweet this comment Submit Comment Subscribe to None Replies All new comments Comments by IntenseDebate Enter text right here! Reply as a Guest, or login: Login to IntenseDebate Login to WordPress.com Login to Twitter Go back Tweet this comment Connected as (Logout) Email (optional) Not displayed publicly. Name Email Website (optional) Displayed next to your comments. Not displayed publicly. If you have a website, link to it here. Posting anonymously. Tweet this comment Cancel Submit Comment Subscribe to None Replies All new commentscenter_img Argonia4947—24 Cunningham: N. Huhman 17, Early 12, C. Huhman 8, Schaller 17, Sterneker 2, Chambers 17, Cannon 1, Hageman 3. Totals 29 (5) 14-21 77.Argonia: Koerner 5, Tracy 4, Dolley 8, Swart 5, Harsh 2. Totals 8 (1) 7-13 24.Wichita Trinity 71 Belle Plaine 43 Trinity A.13211517—66 B. Plaine711914—41 Trinity A.15252110—71 Cedar Vale-Dexter: Sweaney 9, Ames 13, Holingshed 4, Massey 6.Oxford: Patterson 2, Williams 16, Burkes 23, Norris 5, Palmer 3, Kennedy 2. Andale — J. Hermreck 14, B. Seiler 13, G. Deaver 12, B. Knoblauch 10, D. Carney 8, L. Macari 4, A. Roe 3, H. Knoblauch 2, C. Reichenberger 2,Wellington — N. Becker 8, B. Peck 6, A. Weiss 5, N. Wolff 3, L. Woodbridge 2, B. Miles 2.Junior Varsity girls: Wellington 43 Andale 35Carlie McComb 12, Shelby Hamel 11, Kelsey Whaley 9, Avery Lewellen 4, Holly Wright 4, Jaedyn Ledesma 3.Junior Varsity boys: Wellington 43 Andale 38Albright 11, Dunn 11, Nance 11, Phelps 9, Reichenberger 2.C Team girls: Andale 40 Wellington 10Noelle Wright 5, Kennedy Hackerott 4, Dietra Sober 1.C team boys: Andale 62 Wellington 37Phelps 12, Gilmore 10, Jones 6, Lowe 6, Blue 4.Sumner County varsity scores: Boys:South Haven 60, South Barber 54 Conway Springs — B. Pauly 14, S. Echelberry 9, B. May 7, C. Ebenkamp 6, A. Smith 6,Garden Plain — C. Bourne 10, A. Heimerman 8, L. Costello 7, N. Dooley 5, C. Haukap 2, A. Klein 2,Argonia 67, Cunningham 41 South Barber9211014—54 Argonia12161722—67 Conway12111315—51 South Barber: Allison 10, Hitchcock 7, Thurman 4, Reeves 3, Yandel 23, Donaldson 2, Roberts 3, Girty 2. Totals 17 (5) 15-21 54.South Haven: Lowe 14, Harris 2, Yunker 5, Hawkins 5, Cully 9, Byers 14, Ray 9, Moreland 2. Totals 21 (5) 13-26 60.Cunningham 77, Argonia 24 Girls:Trinity Academy 66, Belle Plaine 41 Conway Springs — T. Echelberry 23, R. Rasmussen 11, R. Pauly 5, D. Murphy 5, N. Oswald 4, D. Murphy 3,Garden Plain — T. Bugner 10, C. Milford 8, N. Schumacher 7, T. Puetz 6, D. Doyle 6, M. Panek 2, N. Thimesch 1,Oxford 51, Cedar Vale-Dexter 32last_img read more

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Technique strengthens buildings using wood waste

Citation: Technique strengthens buildings using wood waste (2018, April 13) retrieved 18 July 2019 from https://phys.org/news/2018-04-technique-wood.html Concrete from wood Wood waste from furniture factories makes up a huge portion of waste generated in Singapore. In 2016 alone, more than 530,000 tonnes of wood waste were produced, of which, a significant amount is in the form of saw dust. Instead of incinerating or disposing them in landfills, wood waste can be recycled to make biochar, a porous, carbon-rich material that absorbs and retains water well. Due to its good water absorption and retention properties, biochar is largely employed in the agricultural industry as soil amendment to improve crop yield. Associate Professor Kua Harn Wei, his Ph.D. student, Mr Souradeep Gupta, and their team from the Department of Building at NUS School of Design and Environment further expanded the application of biochar by successfully using biochar recycled from saw dust to significantly improve the mechanical and permeability properties of concrete and mortar.The improvement in the performance of concrete and mortar is achieved by adding a small amount of dry biochar powder into the concrete or mortar mixture. The added biochar alters the conditions in the mixture and enhances the curing and hardening of the mixture.In the experiments, the researchers found that improvement in early strength and impermeability of the concrete and mortar mixture can reach up to 20% and 50% respectively. This can facilitate early removal of formwork, which substantially saves construction time and cost. Furthermore, biochar itself ‘locks in’ carbon in its structure, which would otherwise be released to the atmosphere by decay or by incineration of biomass. The use of the biochar technology in concrete construction is therefore a novel and innovative way to store carbon in buildings while promoting recycling of wood waste and strengthening building structures.Assoc Prof Kua, said, “This is a simple and affordable strategy to enhance our building structures, particularly in Singapore, where water leakage from rain and water pipes are common problems. At the same time, we are putting the large amount of wood waste generated in Singapore into good use. Close to 50 kilograms of wood waste can be utilised for every tonne of concrete fabricated. We typically require 0.5 cubic metre of concrete for every square metre of floor area built in Singapore. This translates to around six tonnes of wood waste being recycled to build a residential apartment with a floor area of 100 square metres.” The NUS team is currently in discussion with a local firm to explore the commercialisation of this technology, and is also leveraging this technology to develop other high performance cement composites with a wide range of applications. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Researchers from the National University of Singapore (NUS) have found an innovative and environmental-friendly technique to enhance building structures. The new method, which incorporates biochar recycled from saw dust into cement, improves the strength and water tightness of mortar and concrete, and offers an alternative use to the large volume of wood waste produced in Singapore. Provided by National University of Singapore Credit: National University of Singapore Explore further read more

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UK teen who hacked CIA chief gets twoyear prison term

Citation: UK teen who hacked CIA chief gets two-year prison term (2018, April 20) retrieved 18 July 2019 from https://phys.org/news/2018-04-uk-teen-hacked-cia-chief.html Kane Gamble, 18, founder of Crackas With Attitude, will serve his sentence in a youth detention facility.”This was an extremely nasty campaign of politically motivated cyber terrorism,” judge Charles Haddon-Cave said at the sentencing at London’s Old Bailey criminal court.”The victims would have felt seriously violated,” Haddon-Cave said, adding that Gamble had “revelled” in the attacks.Gamble was accompanied by his mother in court.He was 15 and 16 when, from his bedroom in Coalville, central England, he managed to impersonate his targets to get passwords and gain highly sensitive information.He impersonated then Central Intelligence Agency chief John Brennan in calls to the telecom companies Verizon and AOL.Several sensitive documents were reportedly obtained from Brennan’s private email inbox and Gamble managed to get information about military and intelligence operations in Iran and Afghanistan.”It also seems he was able to successfully access Mr Brennan’s iCloud account,” prosecutor John Lloyd-Jone said earlier.Gamble called AOL and initiated a password reset, and took control of the iPad of Brennan’s wife.Gamble also targeted then US secretary of homeland security Jeh Johnson and made calls to his phone number.He left Johnson’s wife a voicemail saying “Am I scaring you?” and managed to get a message to appear on the family television saying: “I own you”.Other targets included then US president Barack Obama’s deputy national security adviser Avril Haines, his senior science and technology adviser John Holdren, and FBI special agent Amy Hess.Gamble gained extensive unauthorised access to the US Department of Justice network and was able to access court case files, including on the Deepwater oil spill.The British teenager gave some of the material he managed to access to WikiLeaks and boasted that he had a list of all Homeland Security employees.Gamble was arrested at his home on February 9 last year at the request of the FBI.He claimed he was motivated to act out of support for the Palestinians, and due to the United States “killing innocent civilians”, the prosecutor said. © 2018 AFP Explore further UK teen pleads guilty to hacking CIA chief’s computer A British teenager who accessed the email accounts of top US intelligence and security officials including the head of the CIA was sentenced to two years in prison on Friday. “This was an extremely nasty campaign of politically motivated cyber terrorism,” judge Charles Haddon-Cave said at the sentencing of kane Gamble at London’s Old Bailey criminal court for accessing email accounts of US intelligence officials This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. read more

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